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Each subgroup included three to five animals

10.1016/j.ejmech.2021.113359 137 LiuT.JiangL.TavanaO.GuW

Mounjaro extends to 30 days

Impaired mitophagy contributes to inflammation as the inability to turnover mitochondria in a timely manner increases levels of ROS and damaged mtDNA, with the latter likely to stimulate the cGAS-STING pathway to increase interferon signaling